Arsenal v Blackburn Rovers (Saturday, 3pm)
• Blackburn striker Roque Santa Cruz will miss the trip to the Emirates due to a knee injury. Defender Gaël Givet (knee) is also doubtful while Rovers are monitoring the fitness of winger Morten Gamst Pedersen, who has a rib problem. Vince Grella (groin) is absent and knee-injury victims Brett Emerton and Steven Reid have already been ruled out for the rest of the season.
Blackburn (from): Robinson, Brown, Bunn, Ooijer, Khizanishvili, Nelsen, Samba, Simpson, Warnock, Givet, Olsson, Villanueva, Tugay, Andrews, Diouf, Treacy, Mokoena, Dunn, Haworth, McCarthy, Roberts, Pedersen.
Manchester United v Liverpool (Saturday, 12.45pm)
• Spanish winger Albert Riera will return to the Liverpool squad having been suspended for the midweek victory over Real Madrid, but midfielder Yossi Benayoun is still out with a hamstring injury, as Liverpool try to give Rafael Benitez his 100th Premier League win as Anfield manager. Fernando Torres and Steven Gerrard were both withdrawn in the final stages of the triumph over Real, to protect them for the Old Trafford game. Daniel Agger is unlikely to have recovered from his back injury.
Liverpool (from): Reina, Arbeloa, Skrtel, Carragher, Hyypia, Aurelio, Dossena, Babel, Mascherano, Gerrard, Alonso, Kuyt, Torres, Lucas, Cavalieri, Ngog, Riera, Insua, Spearing, El Zhar.
• The Manchester United manager Sir Alex Ferguson will make changes after the defeat of Internazionale, with Tevez, Park Ji-sung and Anderson among those who could return. Read more on Ferguson's eager anticipation of Liverpool's visit to Old Trafford.
Sunderland v Wigan Athletic (Saturday, 3pm)
• Antoine Sibierski is Wigan manager Steve Bruce's only injury doubt. Sibierski pulled up in training yesterday with a hamstring problem and is unlikely to figure as Wigan look to arrest a run of eight games without a win. New signing midfielder Won-Hee Cho, acquired as a free agent after he let his contract expire with Suwon Blue Wings, could come into contention, with Bruce to make a judgment on his fitness.
Wigan (from): Kirkland, Melchiot, Scharner, Bramble, Figueroa, Cattermole, Watson, N'Zogbia, Valencia, Kapo, Zaki, Mido, Kingson, Pollitt, Edman, Brown, Boyce, Rodallega, Sibierski, Koumas, Cho.
Bolton Wanderers v Fulham (Saturday, 3pm)
• Bolton manager Gary Megson has no new injury worries as he selects from a virtually fully fit squad for the visit of Fulham. The nine-day break since the 2-0 defeat at Stoke has allowed players to get over minor knocks and niggles. Joey O'Brien (knee) remains a long-term absentee.
Bolton (from): Jaaskelainen, Steinsson, Cahill, A O'Brien, Samuel, K Davies, McCann, Basham, Muamba, Gardner, Taylor, Cohen, Makukula, Puygrenier, Obadeyi, Al Habsi, M Davies, Smolarek, Riga, Hunt, Elmander.
• Fulham's centre-back Aaron Hughes faces a spell on the sidelines after sustaining a rib injury during the nidweek defeat to Blackburn. Toni Kallio, who replaced Hughes in that match, could start in his place, while striker Bobby Zamora may be back from the hip problem which kept him out on Wednesday.
Fulham (from): Schwarzer, Pantsil, Stoor, Hangeland, Konchesky, Baird, Davies, Etuhu, Dacourt, Murphy, Gera, Dempsey, Johnson, Zamora, Zuberbuhler, Kallio, Nevland, Kamara, Gray, Barnes.
Middlesbrough v Portsmouth (Saturday, 3pm)
• Portsmouth caretaker manager Paul Hart is expected to field an unchanged side against Middlesbrough. Richard Hughes is available after a hamstring injury and Marc Wilson has recovered after suffering with mumps, but Hart, who will remain in charge for the rest of the season, has so far been reluctant to change his starting line-up during his short stint in charge. Senegal international Papa Bouba Diop is back in light training after two months on the sidelines with a knee ligament injury but is not ready for the first team yet, and Greek striker Theo Gekas must continue to wait for his chance.
Portsmouth (from): James, Johnson, Campbell, Distin, Hreidarsson, Pennant, Davis, Mullins, Kranjcar, Nugent, Crouch, Basinas, Belhadj, Utaka, Kaboul, Kanu, Traoré, Hughes, Wilson, Begovic.
Hull City v Newcastle United (Saturday, 3pm)
• Newcastle captain Michael Owen returns to the squad for the first time since January for the trip to Hull. The 29-year-old is included after recovering from ankle ligament damage and will be joined by the fit-again Nicky Butt (knee) and Damien Duff (calf).
Midfielder Kevin Nolan completes his three-match ban, while Habib Beye (ankle) and Danny Guthrie (hamstring) are closing in on returns. Striker Mark Viduka (achilles) is still two weeks away, and Joey Barton and Xisco (both fractured toe) and Ignacio González (Achilles) remain on the sidelines.
Newcastle (from): Harper, Forster, Krul, S Taylor, Bassong, Coloccini, Enrique, Edgar, Cacapa, Butt, Duff, R Taylor, Gutiérrez, Lovenkrands, Geremi, Donaldson, Ameobi, Smith, Martins, Owen, Carroll.
Chelsea v Manchester City (Sunday, 4pm)
• Midfield duo Vincent Kompany and Nigel de Jong will again be missing as Manchester City look to record their first Premier League away win since August. Kompany (toe) may be fit in time for next week's Uefa Cup second leg against Aalborg but De Jong joins Craig Bellamy on the sidelines with a knee injury. Manager Mark Hughes may opt to keep the side that beat Aalborg last night, as Shaun Wright-Phillips and Wayne Bridge both return to Stamford Bridge for the first time since joining City.
Manchester City (from): Given, Hart, Schmeichel, Richards, Onuoha, Dunne, Bridge, Garrido, Zabaleta, Wright-Phillips, Elano, Caicedo, Ireland, Fernandes, Vassell, Weiss, Robinho, Evans, Bojinov, Logan, Berti.
