Immanuel Feyi-Waboso has been ruled out of England’s forthcoming pursuit of the triple crown and is a major doubt for the rest of the Six Nations tournament, while Steve Borthwick has fitness concerns over George Furbank and Ellis Genge as his team seek to end their Murrayfield hoodoo on Saturday.

Feyi-Waboso pulled out of the 48‑7 victory against Wales 24 hours before kick-off after sustaining a hamstring injury and was replaced by Tom Roebuck. The Exeter winger will be out for “a number of weeks”, ensuring he misses the trip to Murrayfield and the visit of Ireland to Twickenham a week later. He has not yet been ruled out of England’s entire campaign but the chances of him appearing seem remote and he has been left out of the 36‑man squad called into camp on Sunday night.

“Manny looks like he will be out for a number of weeks,” Borthwick said. “We’ve got to get specialist opinion before I know exactly how many weeks he is, but [it’s] a number [of weeks], which is disappointing.”

Furbank sustained a head injury in training and must pass the return‑to‑play protocols if he is to face Scotland. He has not played for England since November 2024 but Borthwick had hoped to have the Northampton full‑back available for the Calcutta Cup. Billy Sela also has a head injury and has been replaced in the squad by George Kloska.

Genge was replaced by Bevan Rodd at half-time against Wales. The Bristol loosehead prop was deemed fit to start but Borthwick admitted afterwards that he was only going to play 40 minutes amid suggestions Genge was carrying a hamstring niggle.

In better news for the head coach, the Bath centre Ollie Lawrence is in contention to face Scotland while the Northampton fly-half Fin Smith is also in the frame after both players returned to the squad. Max Ojomoh has dropped out as a result.

England are on a run of 12 successive wins going in to the meeting with a Scotland team who were beaten by Italy on Saturday, but they have won at Murrayfield only once since 2016. Borthwick is expecting an aerial bombardment with poor weather forecast for the weekend and he has predicted Gregor Townsend will recall Blair Kinghorn to the side.

“From what I hear, they went for a huge number of contestable kicks [against Italy], that was their strategy,” Borthwick said. “And if I reflect on how they played against us last year, there will be a mammoth amount of contestable kicks.

“Potentially, they are going to pick Kinghorn. He may come back into the team because he’s so good in the air. I reckon that’s the challenge we’ll probably face. If you look historically over the last number of years, that’s exactly what Scotland have chosen to do against England.”

Two years ago England began brightly before succumbing to a Scotland comeback, prompting some soul-searching during a training camp in York. The second-row Ollie Chessum has warned his teammates to expect hostility from the moment they arrive at Murrayfield. “It’s a huge challenge,” Chessum said. “I love going up there, the hostility of the place only adds to the fire. You get off the bus at Murrayfield and there are just people on top of you, there is a tone. Once you hear that boo it just hits you in the face and it doesn’t stop until the whistle goes.”

While England are unbeaten in 12 months, their most impressive wins under Borthwick have either come at Twickenham or on neutral territory during the 2023 World Cup. A statement victory on away soil has so far eluded them, something that has not been lost on the back-row Ben Earl.

“You can sometimes lose sight of yourself and be like ‘let’s do a smash-and-grab plan’, or talk about the crowd and all that stuff, but at the end of the day if you play well you’ve got a good chance of winning,” he said. “We’re a slightly different team now and have developed the scar tissue for however long we’ve had this journey, started a bit of a roll and got a bit of momentum.”

George Ford has called on England to embrace their impressive run of form, suggesting previous teams have been reluctant to lean into the confidence that comes with an unbeaten stretch. “We’ve got to definitely use it, it’s such a positive thing, why wouldn’t we use it? I think a lot of the time in England we get told to temper it all the time, but let’s use it. We feel like we’re a good team, we feel like there’s improvement but let’s back ourselves and keep going for it.”