Wasps preserved their slim chance of Heineken Cup qualification next season but their emphatic victory over bottom club Bristol came at a cost. England internationals Paul Sackey and Tom Rees both went off injured during the first half of a seven-try Premiership match.

Their latest setbacks come only two days before Wasps manager Ian McGeechan announces the Lions squad to tour South Africa this summer.

Lions watchers gleaned little from the action at the Memorial Stadium, although both fly-half Danny Cipriani and lock Simon Shaw did their best to nudge McGeechan. Cipriani scored Wasps' decisive second try – he also slotted four conversions and a penalty – while Shaw delivered an industrious contribution in the loose. But Wasps, having surrendered their Premiership title almost three weeks ago, still look unlikely to make the English cut for Europe.

They must beat Gloucester next weekend to have any hope of finishing seventh, yet that still would not be enough if semi-finalists Northampton, Saracens or Worcester win the European Challenge Cup next month.

Wasps can have few complaints if they fail to qualify, having won only 10 of their 21 Premiership games this season.

Wing Josh Lewsey, scrum-half Joe Simpson (2) and flanker Serge Betsen also added tries for the visitors – Simpson's first a superb 60-metre solo effort – with Bristol restricted to two Ed Barnes penalties before substitute forward James Phillips and wing Lee Robinson added late touchdowns, with Barnes kicking one conversion.