Sir Alex Ferguson will check on the fitness of Rio Ferdinand and Jonny Evans before finalising his Manchester United team to face Wigan at the JJB Stadium tomorrow.
Ferdinand tweaked a calf in training on Saturday that ruled him out of United's win over Manchester City, while his replacement Evans limped off with a hamstring injury.
John O'Shea will play in central defence if both are ruled out and Ferguson is also expected to make other changes; Paul Scholes, Michael Carrick and Wayne Rooney among those set to return as United chase the four points required to clinch the title.
Manchester Utd (from): Van der Sar, Foster, Kuszczak; Rafael, O'Shea, Neville, Ferdinand, Vidic, Evans, Evra; Ronaldo, Nani, Carrick, Scholes, Fletcher, Anderson, Park, Giggs; Rooney, Tevez, Berbatov, Macheda.