Northampton v Harlequins
Kick-off 12pm today
Venue Franklin's Gardens
Last year Northampton 13 Harlequins 13
Last five matches North: WWLLL Quins: LWWLW
Northampton, with three defeats in a row, have been hit hard by international call-ups in the past fortnight and Chris Hyndman lines up alongside John Leslie in their centre. Quins give a debut to another three-quarter, the 19-year-old Andy Reay.
Bath v Bristol
Kick-off 2.15pm tomorrow
Venue Recreation Ground
Last year Bath 15 Bristol 9
Last five matches Bristol: WLLWW Bath: LLLWW
Bath have had something of a revival of late but Mike Catt's hamstring injury continues to dog the fly-half. Chris Malone deputises in the West Country derby and England's Mike Tindall and Danny Grewcock may be on the bench. David Rees is expected to replace Bristol's England wing Phil Christophers.
Gloucester v Leeds
Kick-off 2.30pm tomorrow
Venue Kingsholm
TV Sky Sports 2, 2pm
Last year Gloucester 58 Leeds 17
Last five matches Gloc: WLWWL Leeds: WWWDW
First meets second but the leaders Gloucester are smarting from their defeat at Leicester nine days ago and Marcel Garvey, injured at Welford Road, will not play. Tom Beim is a likely deputy. Leeds, beaten only once, give fitness tests to the back-rows Isaac Feaunati and Dan Hyde this morning.
London Irish v Leicester
Kick-off 3pm tomorrow
Venue Madejski Stadium
Last year L Irish 15 Leicester 30
Last five matches Irish: LLWLL Leic: WWWWW
The Exiles, who have slipped to the bottom of the Premiership, name the squad that lost at Bristol. Leicester, with five victories in a row and flexing their considerable muscle, will give Peter Short a run in the pack.
Saracens v Newcastle
Kick-off 3pm tomorrow
Venue Vicarage Road
Last year Saracens 19 Newcastle 24
Last five matches Sara: LLLWL Newc: LWLLL
Ben Johnston's return to the Saracens backline is a welcome boost for their long-suffering supporters but they should record a win against a Falcons side who are suffering an indifferent season and will be without Richard Arnold and Mark Wilkinson.
Wasps v Sale
Kick-off 3pm tomorrow
Venue Adams Park
Last year Wasps 21 Sale 40
Last five matches Wasps: LWLDL Sale: LLWLW
Lawrence Dallaglio will make an appearance for Wasps, provided he recovers from any contribution he may make at Twickenham today. Sale are unchanged from the side that beat Saracens but have still not won away, and Wasps are unbeaten in Wycombe.
