England are chasing a new world record today, having won 17 successive Tests at 'Fortress Twickenham' and now require only one more victory to set an all-time best for consecutive successes at one venue.
England have made one enforced change from the 32-31 win over Australia, as James Simpson-Daniel, who has impressed in the last two Tests, has caught the snogging disease - glandular fever.
His illness means that Bristol wing Phil Christophers is given his second international start.
Prop Jason Leonard lines up for the 99th time in a Test match, while replacement Austin Healey will become the 14th member of England's 50-cap club if he makes an appearance.
South Africa field only one survivor from the side beaten 29-9 at Twickenham last season - Western Province wing Breyton Paulse.
The heavy early morning rain has cleared and blue skies and bright sunshine are greeting the sides in front of another 75,000, Land-of-Hope-and-Glory-singing capacity crowd,
Kick-off 2.30
Teams
England: Robinson, Cohen, Greenwood, Tindall, Christophers, Wilkinson, Dawson, Leonard, Thompson, Vickery, Johnson (c), Kay, Moody, Back, Hill Replacements: Regan, Morris, Grewcock, Dallaglio, Gomersall, Healey, Stimpson
South Africa: Greef, Paulse, Fleck, James, Lombard, Pretorius, Conradie, Roux, Dalton, Carstens, Labuschagne, Venter, Krige (c), Wanneneburg, Niekerk Replacements: Van Biljon, Van der Linde, Jordaan, Wentzel, Uys, Jacobs, Russell